Genetic Variation in Nicotine Metabolism Predicts the Efficacy of Extended-Duration Transdermal Nicotine Therapy

Effectiveness of extended-duration transdermal nicotine therapy: a randomized trial.

BACKGROUND Tobacco dependence is a chronic, relapsing condition that may require extended treatment. OBJECTIVE To assess whether extended-duration transdermal nicotine therapy increases abstinence from tobacco more than standard-duration therapy in adult smokers. DESIGN Parallel randomized, placebo-controlled trial from September 2004 to February 2008. Participants and all research personne...

The pros and cons of transdermal nicotine therapy.

OBJECTIVE To review current knowledge of the efficacy, safety and cost of transdermal nicotine therapy for smoking cessation. DATA SOURCES AND STUDY SELECTION 1. Published and unpublished reports of randomised, double-blind trials of at least 12 weeks' duration, in smokers motivated to cease smoking, identified by a search of the MEDLINE database, article and book bibliographies, Current cont...

Tobacco & Nicotine - nicotine as therapy

Nicotine chewing gum in smoking cessation: efficiency, nicotine dependence, therapy duration, and clinical recommendations.

Side effects of transdermal nicotine patches.